What is the role of glucose oxidase in dairy farming

The special period of 21 days before giving birth and 15 days after giving birth is called the perinatal period. During this period, dairy cows have experienced a series of complex physiological processes. such as pregnancy, childbirth, and lactation. The changes and adjustments of the body's nutritional and endocrine functions are very severe. 

This leads to a decline in the immune status of dairy cows and a decrease in disease resistance, so it is often referred to as the pathological stage of dairy cows. If there is a problem with feeding and management, it will induce puerperal fever, ketosis, retained placenta, metritis, laminitis, true stomach displacement, mastitis and other diseases.

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The role of glucose oxidase in dairy cattle breeding

Glucose oxidase is a green and safe food-grade biological enzyme preparation obtained by fermenting specific Aspergillus fungus strains and using advanced purification technology. It is widely used in food, medicine, feed and other industries. Under aerobic conditions, it can catalyze β-D-glucose to gluconic acid and hydrogen peroxide with high specificity. Under the condition of oxygen consumption, it has 4 functions, namely:
1. Catalyze the glucose in the intestinal tract to produce gluconic acid and hydrogen peroxide. When hydrogen peroxide accumulates to a certain concentration, it inhibits the growth and reproduction of harmful bacteria, such as Escherichia coli and Salmonella;

2. Catalyzes glucose to remove oxygen in the intestine, creating an anaerobic environment for the proliferation of anaerobic beneficial bacteria. Remove a large number of free radicals produced by intestinal epithelial cells when animals are in a state of stress, protect the integrity of intestinal epithelial cells, and inhibit the invasion of coccidia and pathogenic bacteria;

3. The generated gluconic acid acts as an acidulant in the intestinal tract, creating an acidic environment, Reduce the pH value in the stomach, activate pepsin, stimulate the growth of lactic acid bacteria, etc., enhance the digestion and absorption of nutrients in the intestinal tract, and reduce diarrhea;

4. Create an acidic environment for the growth of beneficial bacteria, and the proliferation of beneficial bacteria forms a micro-ecological competitive advantage, inhibiting It can prevent the survival of harmful bacteria such as Escherichia coli and Salmonella, control infection, eliminate spoilage substances, and improve the activity of macrophages, thereby improving the immunity of the body.

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Principle of glucose oxidase enzymatic method

After glucose oxidase enters the rumen, glucose oxidase consumes oxygen in the process of interacting with glucose, forming an anaerobic environment in the digestive tract, quickly restoring the normal anaerobic environment in the rumen, multiplying beneficial microorganisms, restoring the ecological balance of the flora, and promoting the fermentation and decomposition of roughage , reducing the production of toxic substances. At the same time, as an oxidoreductase, it assists the liver to metabolize toxins, relieves the inhibition of toxic substances on the reflex activities of the digestive tract, and promotes the normal peristalsis of the fore stomach. It can effectively relieve the common loss of appetite caused by dairy cow perinatal period, calf changing grass and diseases, and also has the functions of preventing afterbirth, reducing the occurrence of metabolic diseases and improving long-term indigestion in dairy cows.

How to add glucose oxidase?

Suggested dosage of glucose oxidase: twice a day, mix 150 g of solid (150 mL of liquid) in the feed or 200 mL in drinking water. When the main symptoms are relieved, such as appetite, stool color and other obvious improvement, the dosage can be reduced by 50% as appropriate.

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